Great post @davidkachalon yeah it’s all about listening to the whole and augmenting it.
Sometimes a rhythmic addition is just the ticket, like this:
I learned from listening to James Cottone that you can do a -45 shake through a whole blues form, changing to the blow 45 over the IV chord. (Just make sure you expel all the air out your lungs!
)
Splits are a lot of fun to use as jump chorus horn-line kind of accompaniment.
Also in the drone kinda sense the -25 is so nice on the I going to the 25 on the IV and 14 on the V. I gotta remember to do that more.
Roly Platt has a great workshop on rhythm playing:
And one of the things that he points out is that playing rhythm well will really help your lead playing, and he demonstrates that principle really convincingly!
I wish Jerry Fierro’s Mudbone album was online - totally different genre - but he does this one part where he’s using a +1 octave pedal and just going from the -3 on the I chord to the the -3’ on the IV chord on a Soul tune, and it sounds like a Moog or something cos it’s so high. So unique.
Anyhow, there are so many options, and I agree it’s tons of fun to be creative, and the key is to always stay QUIET and SUPPORTIVE. 
